From the moment “The Substance” premiered at Cannes 2024, Margaret Qualley became the industry’s most talked-about star. Playing the sinister double of a once-celebrated, now-faded Hollywood icon, she stunned audiences with a performance that held its own alongside seasoned A-lister Demi Moore. But Qualley’s rise didn’t happen overnight—nor was it without challenges. Here are 20 facts that trace her unique journey through the entertainment world.
She has participated in Le Bal des Debutantes
Margaret Qualley attends the 30th Annual Critics Choice Awards at Barker Hangar on February 07, 2025 in Santa Monica, California. (Photo by Frazer Harrison/Getty Images)
Margaret Qualley attended Le Bal des Débutantes, an exclusive event combining elegance, tradition and philanthropy. Held at the Hôtel de Crillon in Paris, this ball marked a significant moment in Margaret’s transition to public life.
Her participation highlighted her connection to high society and showcased her ability to navigate various social circles. In interviews, she mentioned that such experiences helped her gain confidence and better understand the dynamics of the entertainment and fashion worlds, areas where she has since excelled.
First acting role
Margaret Qualley in “Palo Alto” (Source: IMDb)
Margaret’s acting debut came in 2013 with the film Palo Alto, directed by Gia Coppola and based on stories by James Franco. She played a rebellious teenager in a suburban setting charged with emotional tensions. Although her role was small, her performance left a lasting impression on critics, who praised her ability to convey vulnerability and authenticity on screen.
This first step into acting marked the beginning of her transition from model to actress, setting her on a path she would pursue with determination. Palo Alto not only opened doors to future projects but also allowed her to work alongside other emerging talents of her generation, solidifying her position as a rising star in Hollywood.
Inspiration in Jessica Rabbit
Margaret Qualley attends a photocall at the 77th annual Cannes Film Festival at the Carlton Cannes Hotel on May 19, 2024 in Cannes, France. (Photo by Pascal Le Segretain/Getty Images)
Margaret has mentioned in interviews that Jessica Rabbit, the iconic character from Who Framed Roger Rabbit, has been an unexpected source of inspiration for her acting. According to her, the seductive and enigmatic cartoon represents a fascinating mix of confidence, humor and mystery—qualities she aims to project in her performances.
This curious detail speaks to Margaret’s creative approach, finding inspiration in both classic and unconventional sources. It’s a testament to her ability to transform cultural references into tools that enrich her work and make her unique.
She comes from a family of celebrities
Margaret Qualley and Andie MacDowell attend the AFI Awards Luncheon at Beverly Wilshire, A Four Seasons Hotel on March 11, 2022 in Beverly Hills, California. (Photo by Emma McIntyre/Getty Images)
Margaret comes from a family deeply rooted in the entertainment world. She is the daughter of actress Andie MacDowell, known for films like Groundhog Day and Four Weddings and a Funeral. Her father, Paul Qualley, was a model and musician. This artistic heritage undoubtedly influenced her decision to pursue a career in the industry.
She grew up surrounded by creativity but also aware of the challenges fame brings. She has mentioned that her mother instilled in her the importance of humility and hard work—values fundamental to her success.
She is married to producer Jack Antonoff
Jack Antonoff and Margaret Qualley attend the 64th Annual GRAMMY Awards at MGM Grand Garden Arena on April 03, 2022 in Las Vegas, Nevada. (Photo by Emma McIntyre/Getty Images for The Recording Academy)
In 2023, Margaret Qualley married Jack Antonoff, a renowned music producer and frontman of the band Bleachers. Antonoff has worked with artists like Taylor Swift, Lana Del Rey and Lorde, establishing himself as an influential figure in the music industry.
Their relationship has been described as both a creative and personal connection. The two share a love for the arts and mutual respect for each other’s work. Their marriage has captured public attention, making them one of Hollywood and the music world’s most intriguing couples.
Interest in romantic comedies
Margaret Qualley attends the photocall for “Stars At Noon” during the 75th annual Cannes film festival at Palais des Festivals on May 26, 2022 in Cannes, France. (Photo by Pascal Le Segretain/Getty Images)
Although Margaret Qualley has excelled in intense dramas and complex roles, her interest in romantic comedies is noteworthy. In interviews, she has expressed her admiration for the genre, appreciating its ability to explore human relationships in a light yet meaningful way. This interest reflects her desire to diversify her career and connect with a broader audience.
To date, she has not starred in a project that strictly fits this genre, but her natural charisma and ability to convey emotions position her as an ideal candidate. With her growing popularity, it’s only a matter of time before we see her shine in a romantic comedy that blends her artistic sensitivity with her talent for portraying endearing characters.
Participation in video clips
Margaret Qualley attends the “Honey Don’t!” red carpet at the 78th annual Cannes Film Festival at Palais des Festivals on May 23, 2025 in Cannes, France. (Photo by Pascal Le Segretain/Getty Images)
Margaret’s versatility extends to the music world. She has appeared in several music videos, including the iconic “Easy” by Troye Sivan and Kacey Musgraves. Her ability to communicate emotions through gestures and expressions has made these videos memorable visual experiences.
These collaborations have not only expanded her audience but also showcased her ability to transcend artistic genres. In each video, she brings a cinematic quality that elevates the medium and highlights her adaptability to different forms of storytelling. Also, she has also appeared in advertisements such as Kenzo World.
She shares the profession with her siblings
Sarah Margaret Qualley, actress Andie MacDowell, and Rainey Qualley attend the “Monte Carlo” screening at AMC Loews Lincoln Square on June 23, 2011 in New York City. (Photo by Mike Coppola/Getty Images)
Margaret is not the only one in her family to choose a career in entertainment. Her sister, Rainey Qualley, is an actress and singer known by her stage name Rainsford. Together, they have demonstrated that artistic talent runs in the family.
Although they have different styles and trajectories, the Qualley sisters support each other in their respective fields. This family bond has been a source of inspiration and strength for her, who deeply values her connection with her sister in such a competitive environment as Hollywood.
Her father predicted her role in “Once Upon A Time in Hollywood”
Margaret Qualley in “Once Upon a Time in Hollywood” (Source: IMDb)
Paul Qualley, Margaret’s father, made a prediction that would come true years later: that his daughter would one day work with Quentin Tarantino. When Margaret was cast to play a young member of the Manson family in Once Upon a Time in Hollywood, this prediction surprisingly came true.
This story adds an almost mythical element to her career, showing how family support can be a motivating force. The connection between this prediction and Margaret’s eventual success in the project reflects the faith her family has always had in her talent.
Modeling debut
Actress Margaret Qualley attends the “Sidney Hall” Premiere – 2017 Sundance Film Festival at Eccles Center Theatre on January 25, 2017 in Park City, Utah. (Photo by Alberto E. Rodriguez/Getty Images for Sundance Film Festival)
Before rising to fame as an actress, Margaret ventured into modeling as a means to support herself financially while exploring her creative interests. At 16, she signed with IMG Models and debuted on the runways of New York Fashion Week, walking for high-profile brands like Chanel, Valentino and Ralph Lauren. Her distinctive combination of classic elegance and modernity quickly set her apart from her peers.
While she never saw modeling as her ultimate goal, this phase of her life was crucial in developing stage presence and confidence, which she later carried into her acting work. Additionally, her experience in the fashion industry provided valuable connections and a platform that facilitated her transition to film.
Starring in “Maid”
Margaret Qualley in “Maid” (Source: IMDb)
In 2021, Margaret took on the lead role in Maid, a Netflix series based on Stephanie Land’s memoir. Playing Alex, a young mother struggling to escape a cycle of abuse and poverty, Margaret delivered a heart-wrenching performance that resonated deeply with audiences. The series explored themes of resilience, motherhood, and the social justice system, becoming a cultural phenomenon.
Her performance in this brilliant movie was not only critically acclaimed but also established her as one of the most promising actresses of her generation. According to Margaret, the role helped her better understand the struggles of women facing similar circumstances, reinforcing her commitment to using her platform for social change.
She studied at New York University
Margaret Qualley attends the “Kinds Of Kindness” Photocall at the 77th annual Cannes Film Festival at Palais des Festivals on May 18, 2024 in Cannes, France. (Photo by Andreas Rentz/Getty Images)
Before solidifying her acting career, Margaret attended New York University (NYU), where she explored her interest in the performing arts. Although she didn’t complete her studies, her time at this prestigious institution was pivotal to her artistic and personal development.
Her university experience provided her with key tools to refine her acting technique and understand the nuances of the entertainment industry. Her time at NYU also reflects her commitment to education and desire to hone her talent from a solid foundation.
Her favorite role was that of “Maid”
Margaret Qualley in “Maid” (Source: IMDb)
Margaret Qualley has stated that playing Alex in Maid is one of the most meaningful roles of her career. The series allowed Margaret to explore themes such as resilience, inequality, and sacrifice.
The emotional impact of this role was profound, not only for Margaret but also for viewers, who praised her authentic and moving performance. According to the actress, Maid enabled her to grow personally and professionally, solidifying her place as one of the most promising actresses of her generation.
Commitment to social causes
Margaret Qualley poses at the “Blue Moon” photocall during the 75th Berlinale International Film Festival Berlin at Grand Hyatt Hotel on February 18, 2025 in Berlin, Germany. (Photo by Andreas Rentz/Getty Images)
Beyond her artistic career, Margaret has shown a deep commitment to various social causes. She has used her platform to support initiatives related to gender equality, human rights, and combating climate change. Notably, she has worked with organizations such as Planned Parenthood and Greenpeace, demonstrating a conscious inclination toward activism.
This commitment reflects not only her empathy but also her interest in using her influence to create a positive impact in the world. In a Hollywood landscape where celebrities often focus on superficial causes, she stands out for her authenticity and dedication to issues she deeply cares about.
Beginnings in dance
Margaret Qualley attends the 2022 Critics’ Choice Awards at Fairmont Century Plaza on March 13, 2022 in Los Angeles, California. (Photo by Presley Ann/Getty Images for #SeeHer)
Margaret Qualley began her artistic journey in the world of ballet, a discipline that instilled in her a rigorous work ethic and a deep connection to physical expression. From a young age, she studied at the prestigious North Carolina School of the Arts and later secured a coveted apprentice position with the American Ballet Theatre. Despite her natural talent, she felt that her love for ballet wasn’t enough to dedicate her life solely to dance. At 16, she made the bold decision to leave this path and explore other forms of artistic expression.
This early experience in ballet not only shaped her discipline and artistic sensitivity but also left a lasting mark on her approach to acting. Her ability to understand the narrative of movement has been key to her skill in bringing complex characters to life on screen. Her transition from ballet to film and television is a testament to her courage to reinvent herself and her constant pursuit of new ways to connect with audiences.
She has several artistic hobbies
Actress Margaret Qualley attends HBO’s “Native Son” screening at Guggenheim Museum on April 1, 2019 in New York City. (Photo by Slaven Vlasic/Getty Images for HBO)
In addition to acting, Margaret enjoys various artistic hobbies, including painting and writing. These activities are not only a creative escape but also a way to explore her identity outside of acting.
Her inclination toward the arts demonstrates that Margaret is a multifaceted creator capable of expressing herself in multiple ways. These personal interests enrich her work as an actress and help her connect with her characters authentically.
Interest in commercial cinema
Margaret Qualley attends the 92nd Annual Academy Awards at Hollywood and Highland on February 09, 2020 in Hollywood, California. (Photo by Amy Sussman/Getty Images)
Although Margaret has built her career around auteur projects and intense dramas, she does not rule out participating in commercial films. She has expressed a desire to balance her work between independent films and major Hollywood productions, as long as the project has an interesting narrative and well-developed characters.
Her role in Once Upon a Time in Hollywood is an example of her ability to shine in commercial projects without compromising her artistic integrity. This hybrid approach reflects her desire to build a sustainable career while staying true to her vision as an actress.
Collaboration with Quentin Tarantino
Margaret Qualley and Brad Pitt in “Once Upon a Time in Hollywood” (Source: IMDb)
She reached a new level of visibility with her role as “Pussycat” in Once Upon a Time in Hollywood (2019), directed by Quentin Tarantino. Portraying a young member of the Manson Family, her character was a mix of naivety and manipulation. The chemistry between Margaret and Brad Pitt, who played Cliff Booth, was one of the film’s highlights.
Tarantino’s meticulous approach to detail allowed her to explore a facet of her acting ability she hadn’t showcased before. Her portrayal of Pussycat not only captured audience attention but also demonstrated her capacity to excel in large-scale projects with visionary directors.
Recognition in “Fosse/Verdon”
Margaret Qualley in “Fosse/Verdon” (Source: IMDb)
In 2019, Margaret took on the challenging role of Ann Reinking, a legendary dancer and creative partner of Bob Fosse, in the FX miniseries Fosse/Verdon. This role allowed her to combine her dance background with her growing acting skills, resulting in a deeply emotional and technically precise performance. The series, starring Michelle Williams and Sam Rockwell, explored the complexities of personal and professional relationships in the entertainment world.
She not only captured Reinking’s essence but also demonstrated her ability to shine in high-profile productions alongside award-winning actors. Her work in Fosse/Verdon earned critical acclaim and cemented her reputation as an actress with impressive range.
Lana del Rey wrote a song for her
Lana Del Rey and Margaret Qualley (Source: @BuzzingPop)
Singer Lana Del Rey wrote the song “Margaret” in honor of Margaret Qualley and her relationship with Jack Antonoff, a close friend of the singer. The track, part of the album Did You Know That There’s a Tunnel Under Ocean Blvd., captures the emotional connection between the couple and Lana’s perception of their love.
This gesture highlights the close friendship between Margaret and Lana while reinforcing Margaret’s status as a contemporary muse. The song, imbued with lyricism and sensitivity, testifies to how Margaret inspires other artists through her authenticity and charisma.
