According to Deadline, the network has officially ordered a new spinoff series created by Shonda Rhimes and current showrunner Meg Marinis.

The untitled drama is expected to debut during midseason 2027 and will be executive produced by longtime star Ellen Pompeo alongside Rhimes and Marinis.

A Different Setting for the Grey’s Universe

Unlike previous entries in the franchise, the new series will not take place in Seattle or another major metropolitan area. Instead, the story is set at a rural medical center in West Texas, where doctors and staff serve as a critical lifeline for patients located hours away from larger hospitals.

The project also breaks from another established pattern within the franchise. Earlier spinoffs were built around familiar characters already introduced on the flagship show. “Private Practice” followed Kate Walsh’s Addison Montgomery after she left Seattle Grace Hospital for a private clinic in Los Angeles, while “Station 19” was led by Jason George’s Ben Warren after deciding to leave his surgical residency at Grey Sloan Memorial Hospital. The new drama, however, is reportedly being developed around an original ensemble rather than a direct character transition.

Marinis described the project as an opportunity to expand the emotional core that has defined the franchise since 2005 while introducing a fresh setting and new faces. She also noted the personal significance of placing the story in Texas, her home state. Although the series will focus on a new group of doctors, early reports suggest there may still be links to the existing Grey’s universe through returning characters or institutional connections.

Since its debut, “Grey’s Anatomy” has remained one of ABC’s defining scripted dramas and one of the longest running medical shows in television history. Originally developed by Rhimes as a midseason replacement in 2005, it evolved into a global hit and launched multiple spinoffs, web series, and crossover events over the years. ABC renewed the main production for a 23rd season earlier this year.

The announcement arrives shortly after ABC revealed its 2026 and 2027 programming plans, making the new title one of the network’s highest profile upcoming projects. With a rural Texas setting and an entirely new central cast, the upcoming drama appears designed to broaden the scope of the Grey’s franchise while maintaining the emotional storytelling that helped turn the original series into a television institution.